Unités de recherche

BNMS

Biologie du système neuromusculaire

 

Joint Research Team in “Biology of the neuromuscular system
(UPEC-INSERM-EnvA-EFS; Head: F. Relaix)

This large translational Team is focusing on neuromuscular disorders, from basic to clinical research, including pathophysiological studies, animal models modeling, tissue engineering and therapeutic approaches. Five main axis are developed:

- Molecular mechanisms regulating muscle stem cell development and functions, and interactions with the local and systemic environment

- Tissue engineering of musculoskeletal disorders using muscle and mesenchymal stem cells.

- Pathophysiological and clinical research of neuromuscular disorders, including myotonic dystrophies, macrophagic myofascitis and Duchenne muscular dystrophy.

- The veterinary geneticians are also investigating the genetic bases of canine and feline neuro-muscular disorders, with potential applications for both animal and human healths.

- Canine and feline models of human myopathies are also deeply investigated, in particular for the preclinical evaluation of unique therapeutic strategies, such as exon skipping approaches.

 

 

Ce site utilise des cookies pour améliorer l'expérience de navigation et de fournir des fonctionnalités supplémentaires.